18 octobre 2015 ~ 0 Commentaire

A Review of Hot Melt Extrusion Process Technology to Pharmaceutical Products

1. Introduction

To date HME has emerged seeing as a novel processing technology in developing molecular dispersions of active pharmaceutical ingredients (APIs) into many polymer or perhaps/and lipid matrices which has led this technique to demonstrate time controlled, modified, extended, and targeted drug delivery [1-4]. HME has now provided opportunity for use of materials to be able to mask the bitter flavour of active substances. Since the industrial software of the extrusion method back the 1930

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